The Acquisition of Blood and Skin Samples From Normal Volunteers to Support Research Activities on Dermatologic Diseases

Background: -This protocol is concerned with the acquisition of blood, skin, or mucosal samples from healthy volunteers or patients with selected skin diseases to support the basic science and clinical research activities of the Dermatology Branch and other intramural Laboratories and Branches at the NIH Clinical Research Center. Objectives: (Primary) -To allow collection of blood, skin, or mucosal samples from healthy volunteers or patients with selected skin or systemic diseases as needed to support the research activities of our Branch and other Laboratories and Branches. Eligibility: * Healthy individuals (including employees and other patients) and patients with selected skin or other diseases, including individuals of both genders and all racial/ethnic groups. * Patient volunteers must be willing to undergo blood drawing and/or skin/mucosal biopsies. Design: -This is dependent upon the particular investigation for which these samples are needed....

* INCLUSION CRITERIA: Healthy individuals (including employees and other patients), and patients with selected skin or other diseases, including individuals of both genders and all racial/ethnic groups. Patient volunteers must be willing to undergo blood drawing and/or skin/mucosal sampling/monitoring to include non-invasive skin samples. EXCLUSION CRITERIA: Strong family history and/or evidence of keloid formation following surgery or trauma. Children under the age of 18 years. Pregnant women