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Active Not Recruiting
NCT00581633
Acute Salt Handling in Orthostatic Intolerance
Conditions: Postural Tachycardia Syndrome, Orthostatic Tachycardia, Orthostatic Intolerance
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 30
Sponsor: Vanderbilt University
Location: Vanderbilt University Nashville Tennessee
Summary
The investigators will test the hypothesis that patients with chronic orthostatic intolerance or postural orthostatic tachycardia syndrome (OI or POTS) will be unable to conserve urinary sodium as compared to healthy control subjects.
Eligibility Criteria
Inclusion Criteria:
* Diagnosed with orthostatic intolerance by Vanderbilt Autonomic Dysfunction Center (or healthy control subject)
Exclusion Criteria:
* Overt or acute cause for orthostatic tachycardia
* Hypertension (BP\>145/95 or need for anti-hypertensive medications)
* QRS duration \> 120 msec on EKG
* Pregnancy
Source: ClinicalTrials.gov (NCT00581633). StuddyBuddy aggregates publicly available trial information.
