Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)

Conditions: Pulmonary Disease, Chronic Obstructive, Emphysema, Bronchitis, Chronic

Sex: All

Ages: 45 Years – 80 Years

Healthy volunteers: Yes

Enrollment: 10718

Sponsor: Brigham and Women's Hospital

Summary

Chronic obstructive pulmonary disease (COPD) is a long-term lung disease that is often caused by cigarette smoking. The purpose of this study is to evaluate whether certain genetic factors predispose some smokers to develop COPD more than others.

Eligibility Criteria

Inclusion Criteria: * At least 10 pack-years of cigarette smoking (although a of nonsmoking controls is also being enrolled) * Self-designation of non-Hispanic white or African-American Exclusion Criteria: * Other lung diseases (except for asthma in participants with COPD) * Pregnant * Cancer (other than skin cancer) in the 5 years prior to study entry * Received antibiotics for a COPD exacerbation in the 1 month prior to study entry * First- or second-degree relative of a previously enrolled study participant

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT00608764). StuddyBuddy aggregates publicly available trial information.