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Terminated
NCT01367964
Prevention of West Syndrome With Low-dose Adrenocorticotropin Hormone (ACTH)
Conditions: West Syndrome
Sex: All
Ages: 2 Months – 12 Months
Healthy volunteers: No
Phase: NA
Enrollment: 6
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
Location: Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois
Summary
West syndrome (WS) is a specific type of epilepsy (or seizure disorder) that has three features: infantile spasms (type of seizure), loss of milestones, and a specific pattern on electroencephalogram (EEG or brain wave test) called hypsarhythmia. The purpose of this study is to detect pre-hypsarhythmia in infants at high-risk for WS and determine whether treatment with ACTH will prevent WS.
Eligibility Criteria
Inclusion criteria:
* Infants with pre-hypsarhythmia (Type 3 EEG) between 2 months to 12 months of age.
Exclusion criteria:
* Infants with any of the following diagnoses:
* A previous history of infantile spasms;
* Known inborn error of metabolism;
* Other symptomatic epileptic encephalopathy (e.g. Ohtahara syndrome).
Source: ClinicalTrials.gov (NCT01367964). StuddyBuddy aggregates publicly available trial information.
