Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that currently receives radiation and better compare the short-term and long-term benefits of different types of radiotherapy. The data collected from this study will help facilitate research on radiation therapy and allow for collaborative research. The PPCR will collect demographic and clinical data that many centers that deliver radiation therapy already collect in routine operations.

Eligibility Criteria: 1. Patients treated with radiation therapy at one of the participating centers 2. Age \< 22 at time of treatment start. 3. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in the PPCR. 4. Patients may be enrolled regardless of other current local or systemic treatments or disease extent. 5. Patients may be enrolled on the PPCR concurrently with another study or clinical trial.