Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0

Background: \- High blood pressure is a common problem. It can cause heart attacks, strokes, and kidney failure. It affects African Americans more than other racial groups. Data were collected from over a thousand African Americans across the country. The data were put into a database (MH-GRID). The data were about genes, diet, sleep, body mass index. They also cover stress and access to healthy foods and parks. Researchers at NIH will study these data in new ways. They want to learn more about the connection between African Americans and high blood pressure. Objective: \- To study MH-GRID data to find the causes of severe high blood pressure and other cardio-metabolic problems in people of African ancestry. Eligibility: \- African Americans age 30 55 with severe high blood pressure were used in the MH-GRID study. No new participants will be enrolled in this study. Design: \- Researchers will examine data from the MH-GRID study.

* INCLUSION CRITERIA: * The MH-GRID Project s inclusion criteria included AA age 30-55 years * Severe controlled HTN or severe resistant HTN EXCLUSION CRITERIA: * Exclusion criteria involved patients with secondary forms of HTN, primary forms of kidney disease or major co-morbidities (e.g. diabetes, heart failure, end-stage renal failure, HIV, and liver disease) * Children \