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Recruiting
NCT02387255
Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms
Conditions: Abdominal Aortic Aneurysm
Sex: All
Ages: 20 Years – N/A
Healthy volunteers: Yes
Enrollment: 165
Sponsor: Ohio State University
Location: The Ohio State University Medical Center Columbus Ohio
Summary
The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the current, crude method of assessing risk based on measurement of the diameter of the aneurysm. The investigators will also validate the stiffness estimates against gold standard i.e. mechanical testing and histopathology only AAA patients undergoing AAA surgery.
Eligibility Criteria
Inclusion Criteria:
* Must be able to lie flat on their back in the scanner for up to 60 minutes
* Must be able to hold breath for up to 15 seconds
Exclusion Criteria:
* Patients who are claustrophobic
* Patients who are pregnant
* Patients with any unapproved, non-MRI save metal/devices in or on their body
Source: ClinicalTrials.gov (NCT02387255). StuddyBuddy aggregates publicly available trial information.