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Active Not Recruiting NCT02494869

Dose-Response of Aerobic Training in Women at High-Risk for Development of Breast Cancer

Conditions: High Risk for Developing Breast Cancer

Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 75
Sponsor: Memorial Sloan Kettering Cancer Center

Location: Memorial Sloan Kettering Cancer Center New York New York

Summary

This study is being done to look at the effect that different amounts of progressive exercise training has on risk factors associated with developing breast cancer. These risk factors include exercise capacity, body weight, and body composition, as well as the expression of certain genes and levels of inflammatory factors in your breast tissue. The participant will be instructed to self-report the session information to ExOnc staff at or before their next scheduled visit. If the participant's next scheduled visit is greater than 72 hours following an unsupervised session, ExOnc staff may reach out to the participant to retrieve the session information. Unsupervised session details will be source documented by ExOnc staff.

Eligibility Criteria

Inclusion Criteria: * Women at high-risk of breast cancer as defined by one of the following: * Cytologically confirmed atypical hyperplasia * Cytologically confirmed LCIS * Being a carrier for * BRCA1 and/or BRCA2 * Predicted lifetime risk of breast cancer \>20% based on family history) * Predicted 10-year risk of breast cancer of ≥ 2.31% * Predicted 5-year risk of breast cancer ≥ 1.67% * Aged 21 ≤ 80 years old * If a female of child-bearing potential, must not be pregnant or planning to become pregnant during the study. * Women \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT02494869). StuddyBuddy aggregates publicly available trial information.