The Effects of Sleep on Human Microbiota: Implications for Health and Disease

The aggregate of microorganisms inhabiting the human body can be regarded as a dynamic reflector of both healthy and disease states, altering in response to changes in the environment. This may precede clinically detectable disease; and thereby, could be used to predict disease onset and additionally monitor response to treatment and predict prognosis. The primary hypothesis of this pilot study is that the human microbial communities are influenced by sleep and altered in humans with abnormal sleep patterns, and they may ultimately relate to disease risk.

Inclusion Criteria: * Only subjects who are eligible for ongoing IRB-approved studies will be deemed eligible for this protocol. Exclusion Criteria: * Pregnant or breast-feeding women * Subjects who are ineligible for ongoing IRB-approved studies will not be included in this protocol