Low-Dose Total Skin Electron Therapy in Treating Patients With Refractory or Relapsed Stage IB-IIIA Mycosis Fungoides

Conditions: Recurrent Mycosis Fungoides, Refractory Mycosis Fungoides, Stage I Mycosis Fungoides, Stage II Mycosis Fungoides, Stage III Mycosis Fungoides

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 60

Sponsor: Vanderbilt-Ingram Cancer Center

Summary

This clinical trial studies low- dose total skin electron therapy in treating patients with stage IB-IIIA mycosis fungoides that has not responded to previous treatment (refractory) or has returned after a period of improvement (relapsed). Radiation therapy uses high energy electrons to kill tumor cells and shrink tumors. Rotisserie technique is a method in which the patient receives total skin electron therapy while standing on a rotating platform. Giving low dose total skin electron therapy using rotisserie technique may kill tumor cells, while having fewer side effects, and may allow therapy to be repeated in future if clinically indicated.

Eligibility Criteria

Inclusion Criteria: * Biopsy confirmed mycosis fungoides stage IB-IIIA * Skin manifestations of mycosis fungoides that are refractory to or have relapsed on at least one prior therapy, which may include topical steroids * Life expectancy \> 6 months Exclusion Criteria: * Serious medical condition that would make treatment unsafe * Pregnant or lactating patient

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT02702310). StuddyBuddy aggregates publicly available trial information.