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Completed
NCT02812446
Staphylokinase and ABO Group Phenotype: New Players in Staphylococcus Aureus Implant-associated Infections Development
Conditions: Staphylococcal Infection
Sex: All
Healthy volunteers: No
Enrollment: 88
Sponsor: Nantes University Hospital
Location: CHU de Nantes Nantes
Summary
The purpose of this study is to identify bacterial and/or clinical features involved in the pathogenesis of Staphylococcus aureus implant-associated infections (IAI). Materials \& methods: In total, 57 IAI S. aureus and 31 nasal carriage (NC) S. aureus isolates were studied. Staphylococcus aureus genetic background was obtained by microarray analysis. Multilocus sequence typing was performed to determine clonal complexes (CC). Biofilm production was investigated by resazurin and crystal violet methods
Eligibility Criteria
Inclusion Criteria:
* infected patients with S. Aureus IAI infection
* noninfected patients screened for S. aureus nasal colonization at the orthopedic consultation ward
Exclusion Criteria:
* minor
Source: ClinicalTrials.gov (NCT02812446). StuddyBuddy aggregates publicly available trial information.
