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Recruiting
NCT03192267
Early Rheumatoid Arthritis Lung Disease Study
Conditions: Rheumatoid Arthritis
Sex: All
Ages: 19 Years – 90 Years
Healthy volunteers: No
Enrollment: 125
Sponsor: University of Nebraska
Location: University of Nebraska Medical Center Omaha Nebraska
Summary
Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.
Eligibility Criteria
Inclusion Criteria:
* 19-90 years of age
* Able to give informed consent
* Diagnosis of RA by a Rheumatologist using 2010 American College of Rheumatology (ACR) criteria within the past 2 years
Exclusion Criteria:
* Inflammatory arthritis that does not meet 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA)
* Pregnant
Source: ClinicalTrials.gov (NCT03192267). StuddyBuddy aggregates publicly available trial information.
