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Recruiting NCT03223077

Mucosal and Microbiota Changes During Acute Campylobacteriosis

Conditions: Irritable Bowel Syndrome

Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 150
Sponsor: Mayo Clinic

Location: Mayo Clinic Rochester Minnesota

Summary

Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes in gut bacteria and gut mucosal lining during an acute infection can help identify individuals who might be at risk for developing problems in the future.

Eligibility Criteria

Inclusion Criteria: * No abdominal surgery (except appendectomy and cholecystectomy) * Stool culture or Polymerase chain reaction (PCR) positive enteritis with Campylobacter Exclusion Criteria: * History of IBS, Irritable Bowel Disease (IBD) (Crohn's disease or ulcerative colitis), microscopic colitis or celiac disease. * History of gastroenteritis in six months prior to Campylobacter enteritis * Pregnancy

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT03223077). StuddyBuddy aggregates publicly available trial information.