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Recruiting
NCT03223077
Mucosal and Microbiota Changes During Acute Campylobacteriosis
Conditions: Irritable Bowel Syndrome
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 150
Sponsor: Mayo Clinic
Location: Mayo Clinic Rochester Minnesota
Summary
Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes in gut bacteria and gut mucosal lining during an acute infection can help identify individuals who might be at risk for developing problems in the future.
Eligibility Criteria
Inclusion Criteria:
* No abdominal surgery (except appendectomy and cholecystectomy)
* Stool culture or Polymerase chain reaction (PCR) positive enteritis with Campylobacter
Exclusion Criteria:
* History of IBS, Irritable Bowel Disease (IBD) (Crohn's disease or ulcerative colitis), microscopic colitis or celiac disease.
* History of gastroenteritis in six months prior to Campylobacter enteritis
* Pregnancy
Source: ClinicalTrials.gov (NCT03223077). StuddyBuddy aggregates publicly available trial information.