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Completed NCT03397303

Quantification of Nerve Stiffness in Neuropathies

Conditions: Chronic Inflammatory Demyelinating Polyneuropathy, Charcot-Marie-Tooth Disease, Type IA, Anti-MAG Neuropathy

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 36
Sponsor: Nantes University Hospital

Location: Univeristy of Nantes Nantes

Summary

This project aims to understand how nerve mechanical properties are altered in patients with rare peripheral neuropathies . Stiffness of various peripheral nerves will be measured using ultrasound shear wave elastography. Patients will be compared with age-matched controls.

Eligibility Criteria

Inclusion Criteria: * Male or female aged 18 to 65 * Having social insurance status * Having given informed consent * Diagnostic of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), CMT1a or Anti-MAG (peak immunoglobulin M (IGm)\>15,000 BTU) Exclusion Criteria: For controls: * Person staying in a health or social facility * Person unable to understand the protocol and to respect the modalities * Person deprived of liberty * Person of legal age benefiting from a system of legal protection (guardianship, curators or safeguard of justice) * Participation in another biomedical research in progress * Diabetes, history of neuromuscular disease For CIDP: * Person staying in a health or social facility * Person unable to understand the protocol and to respect the modalities * Person deprived of liberty * Person of legal age benefiting from a system of legal protection (guardianship, curators or safeguard of justice) * Participation in another biomedical research in progress * MRC score \< 3 For Charcot-Marie-Tooth type 1 (CMT1) and anti-MAG: * Person staying in a health or social facility * Person unable to understand the protocol and to respect the modalities * Person deprived of liberty * Person of legal age benefiting from a system of legal protection (guardianship, curators or safeguard of justice) * Participation in another biomedical research in progress

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT03397303). StuddyBuddy aggregates publicly available trial information.