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Terminated
NCT03776513
Neuro-cognitive Impact of Juvenile Obesity
Conditions: Pediatric Obesity, Behavior and Behavior Mechanisms, Emotions
Sex: Male
Ages: 12 Years – 17 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 30
Sponsor: University Hospital, Bordeaux
Location: Bordeaux University Hospital Bordeaux
Summary
Recent studies indicate that obese teenagers exhibit memory disturbances. Adolescence represents a crucial period in the development of the hippocampus and the amygdala, necessary for the implementation of memory and emotional functions for the rest of life. Disturbances of the interaction between amygdala and hippocampus during adolescence have been associated with the development of neuropsychiatric disorders. However, the impact of juvenile obesity on functional amygdala-hippocampus connectivity has not been evaluated yet. The main objective of this study is to compare the emotional memory performance and the level of functional connectivity between the hippocampus and the amygdala during the realization of an emotional associative memory task, in obese and control adolescents.
Eligibility Criteria
Inclusion Criteria:
* Experimental group: 12-17 years old boys, BMI\>30 (according to IOTF), right-handed, French secondary school, beneficiary of social security, consent of the holders of parental authority.
* Control group: 12-17 years old boys, BMI\
Source: ClinicalTrials.gov (NCT03776513). StuddyBuddy aggregates publicly available trial information.
