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Recruiting
NCT03877796
Clinical Pre-screening Protocol for Ovarian Cancer
Conditions: Ovarian Cancer
Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 60
Sponsor: Allarity Therapeutics
Location: Moffitt Cancer Center Tampa Florida
Summary
The patient's local archival tumor tissue (FFPE) from original tumor, or from the metastatic tissue, will be collected to potentially identify if they - at a later stage of their disease - will be likely to benefit from treatment with any of the investigational cancer drugs available to Allarity Therapeutics. Data from this study can further be used to explore in a retrospective fashion, sensitivity to other chemotherapeutic drugs previously used in the treatment of their ovarian cancer, to investigate whether or not the DRP® method can predict and confirm the obtained sensitivity to the prior given drugs as well as prospective analyses guiding the Investigators on future treatments.
Eligibility Criteria
Inclusion Criteria:
* Patients with histological confirmed epithelia ovarian cancer
* Patients must have platinum-resistant disease, defined as progression within 6 months after the last dose of platinum-based chemotherapy, or are platinum ineligible.
* Patients have received no more than one prior line of therapy in the platinum resistant or platinum ineligible setting
* FFPE tumor tissue available
Exclusion Criteria:
* Patients who have platinum-refractory disease, defined as progression during the last platinum-based chemotherapy.
* Other malignancy with exception of any stage I and II cancer that is deemed cured by the Investigator
Source: ClinicalTrials.gov (NCT03877796). StuddyBuddy aggregates publicly available trial information.