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Completed
NCT04016402
Imaging to Improve Brain Stimulation
Conditions: Depressive Disorder
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 42
Sponsor: VA Office of Research and Development
Location: VA Palo Alto Health Care System, Palo Alto, CA Palo Alto California
Summary
This study investigates how brains change as a result of a treatment for depression called repetitive transcranial magnetic stimulation (rTMS). People who receive rTMS will have pictures of their brains and brain activity taken by a magnetic resonance imaging (MRI) scanner before and after their treatment, as well as up to three times during the six-week treatment course. These images will be examined to see if the rTMS is placed correctly to help treat their symptoms, and what changes in brain activity are happening during the rTMS treatment
Eligibility Criteria
Inclusion Criteria:
* Veteran beginning TMS therapy for the treatment of MDD at the Providence VAMC Neuromodulation Clinic
* Age between 18 and 80 years
* Able to read, verbalize, understand, and voluntarily sign the informed consent form
* Structured Clinical Interview for DSM-5 (SCID-5) confirmed diagnosis of MDD
Exclusion Criteria:
* Contraindications to MRI (e.g. implanted metal or electronic devices)
* Montreal Cognitive Assessment (MoCA) score \< 26
* Pregnant
Source: ClinicalTrials.gov (NCT04016402). StuddyBuddy aggregates publicly available trial information.