← Back to all trials
Active Not Recruiting
NCT04135846
Alpha-1 Blockade for Alcohol Use Disorder (AUD)
Conditions: Alcohol Use Disorder (AUD)
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 184
Sponsor: Brown University
Location: Brown University Providence Rhode Island
Summary
The goal of this research is to replicate findings previously conducted in a pilot trial and to understand, mechanistically, the role of stress in the development of AUD pharmacotherapies that target noradrenergic blockade.
Eligibility Criteria
Inclusion Criteria:
* Male or female, 18 years of age
* Meet the DSM-5 criteria for AUD
* Desire to reduce or quit alcohol drinking
* Breath alcohol (BrAC) = 0.00 at each visit
* In good health as confirmed by medical history, physical examination and lab tests
* Willing to adhere to the study procedures
* Understand informed consent and questionnaires in English at an 8th grade level
Exclusion Criteria:
* Women who are breastfeeding or /positive urine test for pregnancy
* CrCl\
Source: ClinicalTrials.gov (NCT04135846). StuddyBuddy aggregates publicly available trial information.
