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Active Not Recruiting
NCT04146051
Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)
Conditions: Myasthenia Gravis, Generalized
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 30
Sponsor: Cartesian Therapeutics
Location: Profound Research Carlsbad California
Summary
This is a Phase IIb study to evaluate the safety and preliminary efficacy of Descartes-08 CAR T-cells in patients with Generalized Myasthenia Gravis
Eligibility Criteria
Inclusion Criteria:
* Patient must be at least 18 years of age.
* Patient must have Generalized Myasthenia Gravis at the time of screening.
* Concomitant immunosuppressive drugs must be deemed necessary by the investigator.
* Seronegative Patients are included
Exclusion Criteria:
* Major chronic illness that is not well managed at the time of study entry and in the opinion of the investigator may increase the risk to the patient.
* Patient is pregnant or lactating.
Source: ClinicalTrials.gov (NCT04146051). StuddyBuddy aggregates publicly available trial information.
