Improving Neurological Health in Aging Via Neuroplasticity-based Computerized Exercise

This study is a validation study to evaluate efficacy of a neuroplasticity-based, computerized cognitive training program INHANCE (Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise) to improve neurological and neuropsychological health in older adults.

Inclusion Criteria: * Potential participant must be 65+ years old at the time of study screening. * Potential participant should achieve a score of ≥ 23 on the Montreal Cognitive Assessment (MoCA). * Potential participant must be likely able to compete all primary outcome measures in the judgment of the consenting study staff person. * Potential participant must demonstrate adequate decisional capacity, in the judgment of the consenting study staff member, to make a choice about participating in this research study. * Potential participant must have the visual, auditory, and motors capacity to use the computerized intervention in the judgment of the consenting study staff person. * Potential participant must already have, be willing to obtain, or be willing to travel to locations with WiFi connectivity to complete intervention activities. * Potential participant must be able to communicate in either English or French. Exclusion Criteria: * Potential participant should not have an existing diagnosis of major or minor neurocognitive disorder at screening. * Potential participants with active suicidal ideation with specific plan and intent or suicide-related behaviors within 2 months of consent as measured by the Columbia-Suicide Severity Rating Scale (C-SSRS) * Potential participant should not have a Geriatric Depression Scale (GDS) score of \>10. * Potential participant should not have been treated within 5 years of the date of consent with a computer-based cognitive training program manufactured by Posit Science. * Potential participant should not be participating in a concurrent clinical trial (involving an investigational pharmaceutical, behavioral treatment, medical device or other) that, in the judgment of the Site Principal Investigator, could affect the outcome of this study. * Potential participant may not be pregnant and should not have claustrophobia or implantation with any medical devices above the waist that may concentrate radio frequency fields, or have other medical issues that may frustrate participation in MRI imaging procedures. * Potential participant should not have medical illnesses deemed to interfere with participation in study activities and/or unstable and/or untreated conditions that may affect cognition, including substance abuse/dependence disorders, drugs that interfere with cholinergic function, ongoing chemotherapy or other cancer treatment. * Potential participant who shows signs of intoxication due to current substance abuse (including alcohol and/or illegal drugs) will be excluded.