PANDIA IRIS: Patients With Diabetes and Kidney Failure, an Interdisciplinary Medication Adherence Support Program

Monocentric, randomised, controlled and open study. Subjects will be included prospectively and consecutively and randomly assigned into two groups. Intervention group A will benefit a medication adherence support program during 12 months while intervention group B during 6 months only. Adherence will be monitored using an Electronic Monitoring system (EM, named MEMS®; Aardex Ltd.) during 24 months. At each pharmacy visit, the pharmacist will conduct a semi-structured interview in 15 minutes based on Fisher's sociocognitive model with the patients. A summary of the interview and the adherence graph will be send to the patient' health professionals.

Inclusion criteria: * MDRD or CKD-EPI eGFR ≤60 ml/min/1.73m2 or albumin/creatinin \>30mg/mmol * Type 2 diabetes * At least one medication in the following list : oral antidiabetics and/or statins and/or antihypertensive drugs and/or aspirin * Patients speaking french, english or italian or interpreter present at each pharmacy visit * Patients have to sign the written consent form * Patients have to agree to use the Electronic Monitoring system (EM, named MEMS®; Aardex Ltd) * Complete laboratory exams in the last 6 months: eGFR and HbA1c and (albumin/creatinin ratio or total cholesterol + LDL + HDL) Exclusion Criteria: * Not being able to understand or sign the consent form * Pregnancy * Recent cancer diagnosis * Cognitive disorder * The subject does not manage the treatment alone