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Completed
NCT04252235
Home Air Purification for Eosinophilic COPD
Conditions: COPD, Eosinophilia
Sex: All
Ages: 40 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 178
Sponsor: Beth Israel Deaconess Medical Center
Location: Beth Israel Deaconess Medical Center Boston Massachusetts
Summary
This study evaluates the influence of home air purification on the lung health of adults with eosinophilic COPD. Half of the participants will receive real air purifiers (HEPA filters) and half will receive sham air purifiers.
Eligibility Criteria
Inclusion Criteria:
* Age of 40 years or more
* Physician diagnosis of COPD \[Global Initiative for Obstructive Lung Disease (GOLD) Stage II-IV disease with Forced Expiratory Volume (FEV1)/ Forced Vital Capacity (FVC) ≤70% and FEV1 (% predicted) \=150 cells per μL at screening or in the previous year
* Former smoker with tobacco exposure of \>=10 pack-years
Exclusion Criteria:
* Inability to complete monthly questionnaires
* Inability to perform lung function testing
* Regularly using a portable HEPA air purifier in the home at time of enrollment
* End stage chronic disease with life expectancy \
Source: ClinicalTrials.gov (NCT04252235). StuddyBuddy aggregates publicly available trial information.