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Active Not Recruiting NCT04273542

Interest of Broadband Spectroscopy Analysis by Infrared Laser on Liquid Biopsies in Breast Cancer Screening

Conditions: Breast Cancer Female, BRCA1 Mutation, BRCA2 Mutation

Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 1100
Sponsor: Centre Jean Perrin

Location: Centre Jean PERRIN Clermont-Ferrand Puy de Dome

Summary

The purpose of this study is to validate the interest of broadband spectroscopy analysis (femto/attosecond by infrared laser) on liquid biopsies in breast cancer screening.

Eligibility Criteria

Inclusion Criteria: \*For all participants : * Adult woman capable of giving informed consent to research participation * Affiliation to the French social security system \>For Control cohort: * Woman participating in organised screening or benefiting from individual follow-up, eligible as such for a mammogram \>For Patient cohort: * woman with invasive breast cancer T0N1, T1N0-1, T2N0-1 (histologically proven) at inclusion and before any cancer treatment \>For Exploratory cohort: * woman carrying the BRCA1/2 mutation, followed according to standard recommendations or * woman carrying the BRCA1/2 mutation suffering from in situ BC discovered on biopsy and histologically confirmed Exclusion Criteria: * For all participants : * Refusal to participate * Reluctant or unable to comply with study requirements * Pregnant or breastfeeding woman * History of breast cancer * For Patient cohort \- Patients with Stage III/IV or Bilateral Breast Cancer * For Control cohort: * Invasive breast cancer suspected at mammography before liquid biopsy\* * Mammography classified ACR3 or ACR4 * For Exploratory cohort: * Concomitant breast cancer * At inclusion visit, woman for whom an invasive breast cancer will be suspected at mammography will be include in Patient cohort after an histological proof of cancer

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04273542). StuddyBuddy aggregates publicly available trial information.