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Active Not Recruiting
NCT04273542
Interest of Broadband Spectroscopy Analysis by Infrared Laser on Liquid Biopsies in Breast Cancer Screening
Conditions: Breast Cancer Female, BRCA1 Mutation, BRCA2 Mutation
Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 1100
Sponsor: Centre Jean Perrin
Location: Centre Jean PERRIN Clermont-Ferrand Puy de Dome
Summary
The purpose of this study is to validate the interest of broadband spectroscopy analysis (femto/attosecond by infrared laser) on liquid biopsies in breast cancer screening.
Eligibility Criteria
Inclusion Criteria:
\*For all participants :
* Adult woman capable of giving informed consent to research participation
* Affiliation to the French social security system
\>For Control cohort:
* Woman participating in organised screening or benefiting from individual follow-up, eligible as such for a mammogram
\>For Patient cohort:
* woman with invasive breast cancer T0N1, T1N0-1, T2N0-1 (histologically proven) at inclusion and before any cancer treatment
\>For Exploratory cohort:
* woman carrying the BRCA1/2 mutation, followed according to standard recommendations or
* woman carrying the BRCA1/2 mutation suffering from in situ BC discovered on biopsy and histologically confirmed
Exclusion Criteria:
* For all participants :
* Refusal to participate
* Reluctant or unable to comply with study requirements
* Pregnant or breastfeeding woman
* History of breast cancer
* For Patient cohort
\- Patients with Stage III/IV or Bilateral Breast Cancer
* For Control cohort:
* Invasive breast cancer suspected at mammography before liquid biopsy\*
* Mammography classified ACR3 or ACR4
* For Exploratory cohort:
* Concomitant breast cancer
* At inclusion visit, woman for whom an invasive breast cancer will be suspected at mammography will be include in Patient cohort after an histological proof of cancer
Source: ClinicalTrials.gov (NCT04273542). StuddyBuddy aggregates publicly available trial information.