Natural Cycle Versus Hormone Replaced Cycle

Sex: Female

Ages: 20 Years – 45 Years

Healthy volunteers: No

Phase: NA

Sponsor: Women's Hospital School Of Medicine Zhejiang University

Summary

Recent sutdies indicate that the existence of corpus lutein in the ovary is a key point to prevent preeclampsia, and patients undergoing FET with hormone replaced cycle have no corpus lutein and the absence of corpus lutein significantly increases the risk of preeclampsia in these patients. We aim to conduct a single center randomized controlled non-inferiority trial to compare the live birth rate and gestational hypertention disease rate between the natural cycle and the hormone replaced cycle in women undergoing FET.

Eligibility Criteria

Inclusion Criteria: 1. 20 to 45 years old women; 2. Scheduled to undergo frozen-thawed embryo transfer. 3. Agreeing with the informed consent. Exclusion Criteria: 1. Hypertention disease before embryo transfer; 2. Oocyte or sperm donated cycles 3. Recurrent miscarriage (at least two miscarriage history) 4. Ovulatory dysfunction

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04310683). StuddyBuddy aggregates publicly available trial information.