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Completed
NCT04321200
PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
Conditions: Pediatric ALL, Infant Development, Neurodevelopmental Disorders
Sex: All
Ages: 0 Months – 6 Months
Healthy volunteers: Yes
Enrollment: 166
Sponsor: University of Pennsylvania
Location: Childrens Hospital of Philadelphia Philadelphia Pennsylvania
Summary
Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes. This study will use state of the art sensors combined with machine learning algorithms to develop objective, accurate, easy-to-use tools for the early scoring of deficits and lays the foundation for the early prediction of physical disability.
Eligibility Criteria
Infants, male and female, between 0-6 months (Infants older than 6 months before initial enrollment will be excluded).
* Infants with early brain injury (EBI):
* Hydrocephalus
* Hypoxic-ischemic encephalopathy (HIE)
* Periventricular leukomalacia (PVL)
* Intraventricular hemorrhage (IVH)
* Stroke
* Healthy infants (controls):
o No history of early brain injury (EBI)
* Infants without EBI/risk for future disability:
* Infants without known brain injuries, but with a history of preterm birth less than 32-week gestation with significant medical problems, difficulty eating, or who lack head control at 4 months of age or later will be classified as moderate risk.
Source: ClinicalTrials.gov (NCT04321200). StuddyBuddy aggregates publicly available trial information.