Sleep Spindles and Memory in Rolandic Epilepsy

Conditions: Rolandic Epilepsy, Rolandic Epilepsy, Benign, Centrotemporal Epilepsy, Centrotemporal; EEG Spikes, Epilepsy of Childhood, Epilepsy; Seizure, Epilepsy

Sex: All

Ages: 4 Years – 18 Years

Healthy volunteers: Yes

Phase: NA

Sponsor: Massachusetts General Hospital

Location: Athinoula A. Martinos Center Biomedical Imaging Charlestown Massachusetts

Summary

The investigators are recruiting children with Rolandic epilepsy and children without epilepsy (aged 4 years old and above) for a non-invasive brain imaging study using Magnetic Resonance Imaging (MRI), Magnetoencephalography/Electroencephalography (MEG/EEG), and experimental tasks. The investigators hope to determine the brain circuits and brain rhythms affected in these children and ultimately identify new treatment options for childhood epilepsy patients.

Eligibility Criteria

Inclusion Criteria: * Clinical diagnosis of childhood epilepsy with centrotemporal spikes (CECTS)or Rolandic epilepsy by child neurologist * Ages 4-18 years * Has an EEG with sleep activated centrotemporal spikes * Has had at least 1 focal motor or generalized seizure Exclusion Criteria: * Has abnormal brain MRI * Has other unrelated neurological disease * Unable to have an MRI/MEG due to claustrophobia, history of frequent vomiting, permanent metal in body (braces), or over MRI weight limit: 350lbs

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04569708). StuddyBuddy aggregates publicly available trial information.