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Active Not Recruiting NCT04569773

Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer

Conditions: Endometrial Cancer

Sex: Female
Ages: 18 Years – 50 Years
Healthy volunteers: No
Enrollment: 43
Sponsor: Memorial Sloan Kettering Cancer Center

Location: Hartford Healthcare (Data Collection) Hartford Connecticut

Summary

The purpose of this study is to learn more about the factors that influence decision-making before surgery (distress about cancer and/or reproductive concerns) and the possibility of regret after surgery.

Eligibility Criteria

Inclusion Criteria: * Women aged ≥ 18 and ≤ 50 years * Premenopausal * Endometrioid histological diagnosis * Scheduled for surgical intervention at MSKCC * FIGO grade 1-2, clinical stage I * Disease confined to uterus, no clear evidence of deep (≥50%) myoinvasion on imaging (MRI preferred, ultrasound optional) * Normal ovaries on preoperative imaging * Able to provide informed consent * English-speaking Exclusion Criteria: * Known Lynch syndrome * Prior bilateral oophorectomy * Personal history of hormone receptor-positive breast carcinoma * Increased risk of ovarian cancer identified on the basis of family or personal history * Women currently on hormonal contraception, letrozole, or tamoxifen may not opt-in to AMH * Women who recently underwent ovarian stimulation within the past 3 months may not opt-in to AMH * Women who have pituitary dysfunction (or any pituitary disorders) may not opt-in to AMH * Women who completed chemotherapy within \

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04569773). StuddyBuddy aggregates publicly available trial information.