← Back to all trials
Active Not Recruiting
NCT04569773
Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer
Conditions: Endometrial Cancer
Sex: Female
Ages: 18 Years – 50 Years
Healthy volunteers: No
Enrollment: 43
Sponsor: Memorial Sloan Kettering Cancer Center
Location: Hartford Healthcare (Data Collection) Hartford Connecticut
Summary
The purpose of this study is to learn more about the factors that influence decision-making before surgery (distress about cancer and/or reproductive concerns) and the possibility of regret after surgery.
Eligibility Criteria
Inclusion Criteria:
* Women aged ≥ 18 and ≤ 50 years
* Premenopausal
* Endometrioid histological diagnosis
* Scheduled for surgical intervention at MSKCC
* FIGO grade 1-2, clinical stage I
* Disease confined to uterus, no clear evidence of deep (≥50%) myoinvasion on imaging (MRI preferred, ultrasound optional)
* Normal ovaries on preoperative imaging
* Able to provide informed consent
* English-speaking
Exclusion Criteria:
* Known Lynch syndrome
* Prior bilateral oophorectomy
* Personal history of hormone receptor-positive breast carcinoma
* Increased risk of ovarian cancer identified on the basis of family or personal history
* Women currently on hormonal contraception, letrozole, or tamoxifen may not opt-in to AMH
* Women who recently underwent ovarian stimulation within the past 3 months may not opt-in to AMH
* Women who have pituitary dysfunction (or any pituitary disorders) may not opt-in to AMH
* Women who completed chemotherapy within \
Source: ClinicalTrials.gov (NCT04569773). StuddyBuddy aggregates publicly available trial information.