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Active Not Recruiting
NCT04655963
Brain Stimulation for Improving Cognition in Chronic Stroke (NEPTUNE)
Conditions: Chronic Stroke
Sex: All
Ages: 40 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: Medical University of South Carolina
Location: Medical University of South Carolina Charleston South Carolina
Summary
Few treatments are available for post-stroke rehabilitation. The current study aims to develop a novel, short-term, high-dose repetitive transcranial magnetic stimulation (rTMS) based intervention to improve post-stroke cognitive problems. This study will test the safety as well as changes in cognitive function and brain activation with the administration of an accelerated rTMS protocol in chronic stroke.
Eligibility Criteria
Inclusion Criteria:
* Have right hemisphere ischemic or hemorrhagic stroke within last 6 months chronicity
* Able to perform given cognitive tasks
* No metal implanted in the body
* A negative urine pregnancy test, if female subject of childbearing potential.
Exclusion Criteria:
* Primary intracerebral hematoma or subarachnoid hemorrhage
* Bi-hemispheric ischemic strokes
* Other concomitant neurological disorders affecting motor or cognitive function
* History of seizure disorder
* Preexisting scalp lesion or wound or bone defect or hemicraniectomy
* Substance use disorder
* Psychotic disorders
* Claustrophobia
Source: ClinicalTrials.gov (NCT04655963). StuddyBuddy aggregates publicly available trial information.