"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

Conditions: Chronic Liver Disease and Cirrhosis, Liver Cancer, Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis, Viral Hepatitis B, Viral Hepatitis C, Viral Hepatitis D

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 800

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Location: PU-PH, Directeur de l'UMR_S1110 Unité Inserm d'affiliation : UMR_S1110 Strasbourg

Summary

Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.

Eligibility Criteria

Inclusion Criteria: 1. Patients * diagnosed with chronic liver disease (viral or not) * diagnosed with at least one liver nodule for which a biopsy is planned as part of the care * for hepatobiliary surgery planned as part of care * for locoregional treatment for HCC is indicated 2. Patients able to receive and understand information relating to the study and give their written informed consent 3. Patients affiliated to the French social security system Exclusion Criteria: 1. Minor patients 2. Patients under legal protection, 3. Patients subject to legal protection or unable to express their consent, 4. Patients in a situation of social fragility, 5. Pregnant or breastfeeding woman, 6. No signing of informed consent.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04690972). StuddyBuddy aggregates publicly available trial information.