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Active Not Recruiting NCT04780477

Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer

Conditions: Colon Cancer, Obesity

Sex: All
Ages: 40 Years – 75 Years
Healthy volunteers: No
Phase: NA
Enrollment: 60
Sponsor: Emory University

Location: Rollins School of Public Health, Emory University Atlanta Georgia

Summary

This study tests whether a high-fiber diet based on legumes, such as dry beans, can lead to sustained reductions in obesity and colon cancer risk in persons at highest risk, namely overweight or obese, post-polypectomy patients.

Eligibility Criteria

Inclusion Criteria: * free-living adults 40 to 75 years old * BMI 25-40 kg/m\^2 * able to provide documentation confirming a colonoscopy within 3 years that found ≥1 adenoma \>0.5 cm or a sessile serrated polyp (any) * English speaking * ambulatory, able to pick up food, participate in clinical exams and laboratory tests * able to provide informed consent Exclusion Criteria: * serious and/or unstable medical condition as deemed by study physician * history of colorectal cancer, bowel resection, polyposis syndrome, or inflammatory bowel disease * smoked regularly in the past year * dietary restrictions substantially limiting compliance (e.g., must be willing to be randomized to either diet) * planning on substantially changing usual exercise behavior in the next 6 months * regular or recent use of prescription medication that may alter inflammation markers or gut function as deemed by study physician * pregnant women, breast feeding women, or women planning pregnancy within the year of active study participation

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04780477). StuddyBuddy aggregates publicly available trial information.