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Terminated
NCT04820946
Evolution of DMDD Children and Adolescent
Conditions: Disruptive Mood Dysregulation Disorder, Prognosis Factors, Suicidal Behaviors, Actigraphy
Sex: All
Ages: 10 Years – 25 Years
Healthy volunteers: No
Enrollment: 4
Sponsor: Centre Hospitalier Universitaire, Amiens
Location: CHU Amiens Amiens
Summary
Little is known about the natural course and prognosis factors of inpatients and outpatients with Disruptive Mood Dysregulation Disorder (DMDD). The investigators conducted a cross-sectional study to determine the evolution of a sample of DMDD patients referred to the hospital for suicidal behaviors between 2013 and 2018 in terms of diagnostic stability, psychiatric comorbidity, and psychosocial factors. A group of patients with various episodic mood disturbances was used as a clinical case control group.
In addition to change in DMDD symptoms across time, the investigators examined the onset and persistence of psychiatric comorbidity using the KIDDIE-SADS PL and suicidal behaviors using the Colombia Suicidality Severity Rating Scale. The investigators also examined the persistence of depressive symptoms using the Beck Depression Inventory (BDI-II), the persistence of emotional lability (Affective Lability Scale-18), borderline traits (Abbreviated Diagnostic of Inventory Borderline). Socio-demographic, clinical features and actigraphy-measured sleep characteristics determined between 2013 and 2018 were used to predict the evolution of the DMDD patients and the clinical control group.
Eligibility Criteria
Inclusion Criteria:
* Boys and girls between 10 and 25-year-old
* patients who had been referred to the university hospital of Amiens for suicidal behaviors between 2013 and 2018
* patients who participated to the study "Clinical and actigraphy-measured profiles of inpatient youths with suicidal behavior: exploration of the severe mood dysregulation"
Exclusion Criteria:
* No affiliation to a social security service
* Persons deprived of their liberty as stipulated in article L.1121-6 of the Public Health Code
Source: ClinicalTrials.gov (NCT04820946). StuddyBuddy aggregates publicly available trial information.