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Active Not Recruiting NCT04919434

Intervention to Reduce Exposure to Environmental COntaminant (IRECO)

Conditions: Exposure

Sex: Female
Ages: 18 Years – 30 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 107
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Location: Institut pour l'avancée des biosciences IAB (U1209)/hôpital couple enfant du CHU Grenoble-Alpes Grenoble

Summary

Main objective The intervention study IRECO aims to (1) modify habits of personal care product use for the participants and (2) evaluate the impact of those modification on urinary concentration for the following compounds: phthalates, phenols and glycol ether. Secondary objectives: The secondary objectives of this study aim to evaluate: 1. impact of modification of personal care product on the levels of biomarkers linked to exposure to environmental pollutant other than phthalates phenol and glycol ether (untargeted analysis) and biomarkers related to health (such as inflammatory biomarkers and oxidative stress). 2. hazard perception linked to the exposure to chemical product present in personal care product 3. barriers to change habits allowing to decrease exposure to environmental pollutant on short and long term as well as levers allowing to remove those barriers.

Eligibility Criteria

Inclusion Criteria: * be a women * be older than 18 and younger than 30 * accept to not use or use only the substitute personal care product for 5 days * no know allergy to ingredients in personal care product * no skin or allergy disease * have a medical insurance * live in Grenoble area * speak french fluently * have a freezer to store the urine sample for a week Exclusion Criteria: * being pregnant * working in a job manipulating personal care product * participating in an other study on cosmetics, personal care product, diet or any other study that may affect exposure to the studied chemicals

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04919434). StuddyBuddy aggregates publicly available trial information.