Reflex Excitability in Post-stroke Stiff-Knee Gait

Conditions: Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic, Gait Disorder, Sensorimotor, Gait Disorders, Neurologic, Walking, Difficulty

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: Yes

Phase: NA

Enrollment: 54

Sponsor: MetroHealth Medical Center

Summary

The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait. We use electrical stimulation of the peripheral nerve innervating the rectus femoris for a well-controlled reflex stimulus. We are investigating whether reflex excitability of the rectus femoris correlates with gait kinematics.

Eligibility Criteria

Inclusion criteria: * Aged at least 18 * Premorbidly independent * If post-stroke, mild to moderate impairment determined by standard practices per the physical therapist * Able to continuously walk for 30 minutes * If post-stroke, reduced knee flexion during walking relative to unimpaired side * If post-stroke, hemiparesis * Ability to provide informed consent Exclusion criteria: * No history of serious lower limb musculoskeletal injury * No functionally relevant osteoarthritis and weight-bearing restrictions * No functionally relevant polyneuropathy * No functionally relevant cognitive impairment * No functionally relevant vision impairment

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04947865). StuddyBuddy aggregates publicly available trial information.