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NCT05027789
Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention
Conditions: Memory Disorders, Cognitive Impairment
Sex: All
Ages: 65 Years – 90 Years
Healthy volunteers: No
Phase: NA
Enrollment: 263
Sponsor: University of California, Davis
Location: University of California, Davis Alzheimer's Disease Center Sacramento California
Summary
The purpose of this research is to determine if training in memory support aids and healthy lifestyle activities (physical exercise, mentally stimulating activities and stress management) can have a positive effect on memory, thinking, and activities that people do every day. Participation in this study will involve being placed into one of two groups: a Self-Guided Intervention Group or a Structured Intervention Group. Both groups will be asked to attend group sessions in which they will be provided education on memory support strategies and lifestyle changes. The Structured Intervention Group will also be provided with an iPad and a digital application (called EMMA) to track their activity. Study participation involves a 6-month intervention and completing outcome measures at 4 different time points for up to a year.
Eligibility Criteria
Inclusion Criteria:
* The target population is cognitively normal older adults with Subjective Cognitive Concerns (SCC). SCC will be operationalized as
1. a positive complaint in response to the question: 'Have you experienced a decline in your memory or other aspect of thinking in the last 1-3 years that seems worse than others of your age'
2. normal cognition on the modified Telephone Interview of Cognitive Status (mTICS)
3. independent function in daily life.
* Age 65 or older
* English speaking
* Lower level of engagement in healthy lifestyle behaviors and compensation use at study baseline (i.e., broadly defined as not a regular exerciser)
* Approval from primary care (due to physical exercise component of the intervention)
* Open to utilizing digital tools such as a digital calendar in daily life
Exclusion Criteria:
* Known diagnosis of dementia or cognitive impairment;
* Other known neurological condition with potential to affect cognition (e.g., Parkinson's disease)
* Reported history of severe psychiatric disorder (e.g., self-reported history of bipolar disorder or schizophrenia or other psychotic disorder)
* Inability to complete the study protocols due to severe vision or hearing difficulties.
* Has previously participated in a previous version of Brain Boosters, or another study utilizing the Digital Memory Notebook (DMN) application or EMMA.
Source: ClinicalTrials.gov (NCT05027789). StuddyBuddy aggregates publicly available trial information.