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Completed
NCT05064449
A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults
Conditions: Healthy Volunteers
Sex: All
Ages: 19 Years – 55 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 28
Sponsor: Takeda
Location: Celerion Lincoln Nebraska
Summary
The main aim of this study is to check how itraconazole and mefenamic acid affect the way soticlestat is processed by the body.
The study will have 2 parts. Participants can only participate in one study part.
Part 1: Participants will check into the study clinic to receive soticlestat, four days later they will begin receiving itraconazole and will stay in the clinic for 11 more days, receiving soticlestat in combination with itraconazole on one of those days. Participants will be contacted about 8 days after leaving the clinic for follow-up.
Part 2: Participants will check into the study clinic to receive soticlestat, four days later they will begin receiving mefenamic acid and will stay in the clinic for 7 more days, receiving soticlestat in combination with mefenamic acid on one of those days.. Participants will be contacted about 9 days after leaving the clinic for follow-up.
Eligibility Criteria
Inclusion Criteria:
1. Has body mass index (BMI) greater than or equal to (\>=) 18.0 and less than or equal to (\=90/40 millimeter of mercury (mmHg) and \=45 beats per minute (bpm) and \
Source: ClinicalTrials.gov (NCT05064449). StuddyBuddy aggregates publicly available trial information.