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NCT05136781
DEXAMETHASONE for Non-urgent Thoracic Surgery
Conditions: Thoracic Surgery, Anesthesiology, Corticosteroids, Respiratory Complication
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Sponsor: Centre Hospitalier Universitaire, Amiens
Location: Centre Hospitalier Universitaire d'Amiens Amiens Picardie
Summary
Thoracic surgery is at high risk of respiratory complications. Despite the improvement of surgical procedures such as video-thoracoscopy, respiratory complications appear in 15 to -20% of procedures. Thoracic surgery induces local pulmonary inflammation which is involved in the occurrence of post-operative respiratory failure. Similarly to the example of the acute respiratory distress syndrome, corticosteroids could reduce lung injury secondary to immunological stress. In addition, recent studies suggest that dexamethasone could lead to a reduction of respiratory complications after major non cardiothoracic surgery.
Since dexamethasone is recommended to prevent postoperative nausea and vomiting, around one in two patients receive dexamethasone during anesthetic induction. By retrospective analysis with compensation of bias by propensity score, the investigators aim to assess the effect of dexamethasone to prevent respiratory complications
Eligibility Criteria
Inclusion Criteria:
* age : minimum 18 years old
* Patients who underwent scheduled lung resection surgery
Exclusion Criteria:
* absence of patient's consent
* age under 18 years
* pregnant women
Source: ClinicalTrials.gov (NCT05136781). StuddyBuddy aggregates publicly available trial information.