Healthy Opioid Prescription Engagement

This study is a randomized controlled trial across 14 community pharmacies to test the efficacy of the Brief Intervention-Medication Therapy Management intervention (BI-MTM). The establishment of the BI-MTM model will result in a major impact for addressing the opioid epidemic, preventing opioid use disorder and overdose, and safeguarding patient health in a novel community-based service setting.

Inclusion Criteria: * Adult (≥18 years) * English speaking * Not receiving cancer treatment * Who have a positive opioid misuse screen on the POMI will be eligible to learn about this study Exclusion Criteria: * Are pregnant (given potential pre/post-natal opioid use complications among pregnant women/offspring * Can-not provide collateral contact information for ≥2 contact persons (to ensure consistent contact/follow up) * Do not have a reliable land line or mobile phone to be contacted by study staff * Are filling only buprenorphine (given some formulations are not indicated for pain) * Plan to leave the area for an extended period of time in the next 6 months * Have had a psychotic and/or manic episode in the last 30 days (before consent, patients will be asked to screen for psychosis * Do not provide permission to access their state prescription drug monitoring data.