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Completed NCT05283980

Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement

Conditions: Pain, Postoperative, Pain, Acute, Pain, Chest, Pain, Satisfaction, Patient, Opioid Use, Unspecified, Opioids; Harmful Use

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Phase: PHASE2, PHASE3
Enrollment: 62
Sponsor: Beth Israel Deaconess Medical Center

Location: BIDMC Boston Massachusetts

Summary

The purpose of this study is to determine whether administration of a pectoral nerve blocks (Pecs I and II) with 0.25% bupivacaine are more effective as compared to placebo to provide analgesia for cardiac implantable electronic device (CIED) placement in cardiac electrophysiology lab

Eligibility Criteria

Inclusion Criteria: * Patients 18 years of age or older * Undergoing CIED placement in electrophysiology lab * Booked with anesthesia service for the procedure. Exclusion Criteria: * Current participation in another interventional study * Use of mechanical circulatory support device * Emergent procedures * Patients receiving other modalities of regional anesthesia like intrathecal morphine * Chronic opioid use for chronic pain conditions with tolerance (total daily dose of an opioid at or more than 30 mg morphine equivalent for more than one month within the past year) * Current use of SSRI, TCA, anti-epileptics, gabapentin, or pregabalin as part of multimodal pain management * Hypersensitivity to bupivacaine * Hemodynamics related: Oxygenation outside of normal limits (defined as PaO2 \< 60mmHg on an FiO2 of 1.0 or SpO2 \< 85% within 30 minutes prior to drug administration), Received an infusion or bolus ≥ 0.05 mcg/kg/min of epinephrine o Received an infusion or bolus ≥ 0.50 mcg/kg/min of milrinone, Received an infusion or bolus ≥ 0.20 mcg/kg/min of norepinephrine o Significant clinician or nursing concern, Hemodynamically unstable (defined as HR \> 120, SBP \< 80, MAP \< 50 within 30 minutes prior to drug administration)

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05283980). StuddyBuddy aggregates publicly available trial information.