Sitting Interruption and Whole-body Cardiovascular Health

There is strong evidence for the association between sedentary behaviors and cardiovascular diseases such as coronary heart disease and stroke. However, the public currently has no clear guidance on how to limit or interrupt their sedentary behaviors. This study will identify and test the physiological effects of several sedentary behavior interruption strategies and explore the feasibility (i.e., likelihood of an individual performing the requested activities) of those strategies to inform the development of public policy surrounding sedentary behavior interruption. Long-term, the findings of this study will inform a large clinical trial that can test whether sedentary behavior reduction can decrease cardiovascular disease risk.

Inclusion Criteria: * Aged between 30-60 years * Insufficiently active: self-reported exercise \8 hours per day * Self-reported ability to walk 4 blocks and climb 2 flights of stairs * Possession of cellular phone able to receive text messages Exclusion Criteria: * Use of assisted-walking devices * Comorbid condition that would limit the ability to reduce sedentary behavior (e.g., musculoskeletal condition, current chemotherapy) * Plans for major surgery within next 3 months * Recent history (\40 kg/m\^2) or underweight (BMI \15 drinks per week)