Intravenous vs Oral Acetaminophen in Postoperative Hip Fracture Adult Patients

Sex: All

Ages: 60 Years – N/A

Healthy volunteers: No

Phase: PHASE4

Enrollment: 42

Sponsor: University Health Network, Toronto

Summary

The INTACT-HIP trial study will evaluate feasibility of conducting a randomized, double-blinded controlled trial comparing postoperative treatment with intravenous (IV) acetaminophen versus oral acetaminophen, in older adults undergoing hip fracture surgery. The results of this feasibility trial will be used to inform designing a larger, multi-center, randomized controlled trial to assess the efficacy of IV acetaminophen compared to oral acetaminophen to reduce delirium and improve other clinical and patient-centered outcomes after hip fracture surgery. It will randomize 42 older adults to receive either oral or IV acetaminophen after hip fracture surgery.

Eligibility Criteria

Inclusion Criteria: * 60 years of age and older * Patients who were ambulating without human assistance before fracture, with any type of non-neoplastic hip fracture * Patients undergoing surgical treatment as an inpatient Exclusion Criteria: * Patients with neoplastic hip fracture * Severe cognitive impairment (Montreal Cognitive Assessment (MoCA) \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05425355). StuddyBuddy aggregates publicly available trial information.