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Completed
NCT05442190
Topical SGX302 for Mild-to-Moderate Psoriasis
Conditions: Psoriasis, Plaque Psoriasis, Psoriasis Vulgaris
Sex: All
Ages: 18 Years – 75 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 15
Sponsor: Soligenix
Location: Therapeutics Clinical Research San Diego California
Summary
To evaluate SGX302 (topical hypericin ointment and gel) with visible light in an initial 18-week treatment course for improving lesions in patients with mild-to-moderate psoriasis.
Eligibility Criteria
Inclusion Criteria:
* Have a clinical diagnosis of plaque psoriasis (psoriasis vulgaris) of at least 6-months duration that involves the body (trunk and/or limbs) that is amenable to topical treatment and opaque coverage after application.
* Have a static Investigator Global Assessment (IGA)/Psoriasis Area and Severity Index (PASI) of disease severity of mild or moderate on the body (trunk and/or limbs).
* Have lesions involving 2-30% of the body (trunk and/or limbs). For subjects with scalp psoriasis included in the treatment area, the total treatment area on body and scalp must not exceed 30%.
Exclusion Criteria:
* Use of topical anti psoriatic therapy within one week prior to the beginning of the study and willing to not use other psoriasis treatments for 4 weeks following completion of the treatment portion of the study.
* Received systemic biologic therapy to treat psoriasis within 12 weeks prior to the beginning of the study.
* Received systemic psoriasis therapy within 4 weeks prior to the beginning of the study.
* Received phototherapy (including laser) or photodynamic (light activated drug) therapy within 4 weeks prior to the beginning of the study.
Source: ClinicalTrials.gov (NCT05442190). StuddyBuddy aggregates publicly available trial information.