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Completed NCT05450679

Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes

Conditions: Cervical Facet Joint Pain, Chronic Pain, Neck Pain

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 69
Sponsor: Johns Hopkins University

Location: Johns Hopkins Hospital Baltimore Maryland

Summary

The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or duration of analgesia. The investigators propose a straightforward grading scale based on visual and tactile information readily available during RFA procedures as part of routine practice (per radiofrequency electrode: 0 = no twitches palpated or observed; 1 = twitches palpated but not observed; 2 = twitches palpated and observed at 1-2 levels; 3= twitches palpated and observed at \>2 levels). If a higher weighted score (total score divided by number of radiofrequency lesion sites) correlates with a greater likelihood of treatment success, or magnitude or duration of analgesia following cervical RFA, cervical paraspinal muscle twitching may serve as a readily obtainable prognostic factor (marker) for effectiveness.

Eligibility Criteria

Inclusion Criteria: * Age 18 years or older * Cervical facet arthropathy based on history and physical exam (e.g. axial cervical neck pain, paraspinal tenderness, no pain referral below the ipsilateral shoulder) * Radiologic evidence of cervical pathology consistent with symptoms if MRI is available * Pain duration of greater than 3 months * Obtained 50% or greater pain relief from at least 1 diagnostic cervical medial branch block of the identical medial branch nerves targeted for RFA Exclusion Criteria: * Untreated coagulopathy * Signs or symptoms of cervical myelopathy * Signs or symptoms of cervical radiculitis/radiculopathy * Allergic reactions to local anesthetics * Serious psychiatric disorder (e.g. uncontrolled or refractory depression) that might preclude optimal outcome * Poorly controlled medical condition (e.g. pacemaker that cannot be switched off, unstable angina) * Pregnancy

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05450679). StuddyBuddy aggregates publicly available trial information.