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Completed NCT05503251

Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases

Conditions: Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm

Sex: All
Healthy volunteers: No
Phase: PHASE2
Enrollment: 110
Sponsor: Ohio State University Comprehensive Cancer Center

Location: Ohio State University Comprehensive Cancer Center Columbus Ohio

Summary

This phase II trial studies the effect of neuropsychological evaluation and intervention in maintaining quality of life after radiation therapy in patients with cancer that has spread to the brain (metastases). Quality of life refers to the overall enjoyment of life. It holds varying meanings for different people and may evolve over time. For some individuals it implies autonomy, empowerment, capability, and choice; for others, security, social integration, or freedom from stress or illness. Neuropsychological evaluation is used to examine the cognitive (thinking) consequences of brain damage, brain disease, and severe mental illness. Deterioration of both quality of life and cognitive function is common when receiving radiation to the brain. Neuropsychological evaluation with a certified neuropsychologist may improve quality of life or cognitive function after radiation therapy.

Eligibility Criteria

Inclusion Criteria: * Stage IV histologic diagnosis of solid tumor * Patient will be treated with radiation therapy for brain metastases * Primarily English-speaking patient * Graded Prognostic Assessment (GPA) \>= 2 (estimated survival \> 6 months) Exclusion Criteria: * Patient received prior whole brain radiation therapy to the brain * Patient has multiple sclerosis, Alzheimer's, dementia, or mental disability

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05503251). StuddyBuddy aggregates publicly available trial information.