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NCT05583617
A Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple Myeloma
Conditions: Multiple Myeloma
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE1, PHASE2
Enrollment: 200
Sponsor: Hoffmann-La Roche
Location: Prince of Wales Hospital Randwick New South Wales
Summary
CO43923 is a platform study that will evaluate the safety, efficacy, and pharmacokinetics (PK) of multiple treatment combinations, as monotherapy or in combination, in participants with multiple myeloma (MM). The study is designed with the flexibility to open new treatment substudies as new treatments become available. Information regarding the opened substudies are found below.
Eligibility Criteria
Inclusion Criteria:
* Diagnosed with MM per International Myeloma Working Group (IMWG) criteria
* Eastern Cooperative Oncology Group Performance Status of 0, or 1, or 2
* Resolution of AEs from prior anti-cancer therapy to Grade \
Source: ClinicalTrials.gov (NCT05583617). StuddyBuddy aggregates publicly available trial information.