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NCT05599139
Iodine Uptake After a Low Iodine Diet
Conditions: Differentiated Thyroid Cancer
Sex: All
Ages: 18 Years – 75 Years
Phase: NA
Enrollment: 25
Sponsor: University Medical Center Groningen
Summary
The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days.The main question it aims to answer is:• What is the difference in iodine uptake before and after a LID of 7 days?Uptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days.
Researchers will compare the uptake (%) before and after the LID.
Eligibility Criteria
Inclusion Criteria:Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I ablation therapy according to the Dutch DTC guidelinePatients have to be fit to adhere to the study protocolPatients have to be able to read and understand the Dutch languageExclusion Criteria:Age < 18 yearsPatients using amiodaronePatients receiving iodinated contrast < 3 months before the LIDPregnancyPatients prepared for ablation therapy with rhTSHRenal impairment, EGFR <30ml/min/1,73m2
Source: ClinicalTrials.gov (NCT05599139). StuddyBuddy aggregates publicly available trial information.