Intralesional Injection of Combined Digoxin and Furosemide Versus 5-Flurouracil in Plantar Warts

The aim of the current work is to evaluate the efficacy and safety of intralesional combined Digoxin and furosemide versus intralesional 5-flurouracil in the treatment of plantar warts.

Inclusion Criteria:Patients with multiple plantar warts (≥ 3) will be included.Exclusion Criteria:Patients under 18 years old or patients over 65 years old.Pregnancy or breast feeding.Patients received vaccination or any other treatment of warts during the last month.Patients with a known sensitivity to any of the investigational product ingredients.Patients with history of asthma, allergic skin disorders or convulsions.Patients with signs of any systemic or local inflammation or infection.Patients with any evidence of immunosuppression including HIV.History of cardiac diseases, relevant abnormal K level or ECG abnormalities for patients who will receive the combined digoxin and furosemide.