Screening for Cystic Fibrosis and Cystic Fibrosis Related Disorders in Chinese Adults With Bronchiectasis

The study carries out Sweet Tests and CFTR-mutation screening to explore the prevalence, clinical characteristics, and prognosis of cystic fibrosis, as well as the CFTR-mutation spectrum in Chinese adults with bronchiectasis. The study is multi-centered, prospective, non-interventional, and observational.

Inclusion Criteria:Age>18 years, the diagnosis of bronchiectasis needs a reference to the definition of "non-cystic fibrosis bronchiectasis guideline" published by the British Thoracic Society in 2017 or 2021 China bronchiectasis expert consensus, clinical symptoms of cough and expectoration, with or without intermittent hemoptysis, and chest CT showed bronchiectasisPatients who are willing to sign the consent form and participate in the study.Exclusion Criteria:Patients with incomplete essential information, which is needed for the integrity of data analysis. Essential information includes CT images, respiratory sample cultures, spirometry, and exacerbation history for at least one year.Patients under 18 years old.Sweat Test Exclusion Criteria:Patients with an implanted device, such as a defibrillator, neurostimulator, pacemaker, or ECG monitor.Patients with a history of epilepsy or seizures.Patients who are pregnant.Patients that have a known sensitivity or allergy to any ingredient.Over-damaged, denuded skin or other recent scar tissue.Patients with Cardiac Conditions or with suspected heart problems.