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Completed
NCT05604586
Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance
Conditions: Skeletal Muscle Performance, Gene Polymorphisms
Sex: All
Ages: 18 Years – 45 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 77
Sponsor: Poznan University of Life Sciences
Location: Poznan University of Life Science Poznan
Summary
Study aims to verify the hypothesis:
* N-acetylcysteine (NAC) supplementation improves exercise capacity in people training endurance sports and the effectiveness of this supplementation depends on the polymorphism of genes related to folate and glutathione metabolism.
* NAC supplementation affects the parameters of oxidative stress among women and men training endurance disciplines
Eligibility Criteria
Inclusion Criteria:
* Consent to participate in the study and acceptance of the established scheme for conducting the intervention
* age range between 18 and 45 years old
* regular training with a frequency of at least 3 times a week during the last year,
Exclusion Criteria:
* no consent to participate in the study and no acceptance of the established scheme of the conducted intervention
* existing diseases of the blood system and neoplastic diseases
* respiratory system diseases
* obesity
* any medical contraindications to exercise
* Results obtained from exercise tests that do not meet the inclusion criteria
* use of NAC during the last month
* allergy to NAC
* smoking
* pregnancy and lactation
Source: ClinicalTrials.gov (NCT05604586). StuddyBuddy aggregates publicly available trial information.