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Recruiting
NCT05606068
A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy - Expansion Study
Conditions: Chemotherapy-induced Peripheral Neuropathy
Sex: All
Ages: 21 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 200
Sponsor: National University Hospital, Singapore
Location: National University Hospital Singapore
Summary
The study conducted on cancer patients is designed to test safety and efficacy of limb hypothermia in cancer patients using the new Paxman Limb Cryocompression System (PLCS). Ultimately this will lead to the development of a therapy regime that will help to prevent chemotherapy-induced neuropathy in cancer patients.
Eligibility Criteria
Inclusion Criteria:
* Age 21- 80 years.
* Signed informed consent from patient or legal representative
* Scheduled to receive weekly paclitaxel chemotherapy
* Patients may receive other chemotherapy drugs alongside taxane e.g. Platinum/Herceptin.
Exclusion Criteria:
* Open skin wound or ulcers of the limbs
* History of Raynaud's phenomenon, peripheral vascular disease, or poorly controlled diabetes
* Pregnant woman
* A score of more than 5 in Total Neuropathy Score (TNS) at baseline for cancer patients
Source: ClinicalTrials.gov (NCT05606068). StuddyBuddy aggregates publicly available trial information.
