Genetic of Chronic Kidney Disease and Gout in New Caledonia

The goal of this research is to study the associations of genetic variants of gout and kidney failure, which are very common in the Melanesian population in New Caledonia

Inclusion Criteria:Criteria common to the 3 cohorts :- Consenting to participate in the study and having signed the informed consent- Claiming to be of Melanesian ethnicityPatients with gout :Age: 18 - 70 years oldTo be included in the study, a patient with a diagnosis of gout in his medical file or declaring to have gout will have to satisfy to the ACR/EULAR (ref) classification criteria :have had at least one episode of swelling, pain spontaneous, or triggered by pressure, of a joint peripheral or a bursa AND evidence of sodium urate crystals in a joint or bursitis symptomatic or by puncture of a tophus reported in his medical file.Or Score > or =8 according to ACR/EULAR clinical criteriaPatients with CKDAge: 18 - 70 years oldPatients on dialysis or CKD clinically diagnosed on the basis of:Markers of kidney damage (one or more) : Albuminuria (ACR ≥ 30 mg/g), Urinary sediment abnormalities (e.g., casts urinary), Electrolyte abnormalities and other, abnormalities due to tubular disorders (eg, hyperkalemia), abnormalities detected by histology, structural abnormalities detected by imaging (e.g.,USG), history of kidney transplantationDecreased kidney function: GFR < 60 ml/min/1.73 m² (calculated according to the Chronic Kidney Disease - EPIdemiology formula: CKD-EPI)Controls cohortAbsence of gout or CKDAge: 30 - 80 years oldExclusion Criteria:Pregnant womenIndividuals under guardianship / curatorship / judicially incapacitated